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Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies
HIV-1 Gag selects and packages a dimeric, unspliced viral RNA in the context of a large excess of cytosolic human RNAs. As Gag assembles on the plasma membrane, the HIV-1 genome is enriched relative to cellular RNAs by an unknown mechanism. We used a minimal system consisting of purified RNAs, recom...
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| 出版年: | eLife |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946900/ https://ncbi.nlm.nih.gov/pubmed/27343348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14663 |
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