Loading...
Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies
HIV-1 Gag selects and packages a dimeric, unspliced viral RNA in the context of a large excess of cytosolic human RNAs. As Gag assembles on the plasma membrane, the HIV-1 genome is enriched relative to cellular RNAs by an unknown mechanism. We used a minimal system consisting of purified RNAs, recom...
Saved in:
| Published in: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
eLife Sciences Publications, Ltd
2016
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946900/ https://ncbi.nlm.nih.gov/pubmed/27343348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14663 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|