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Dissection of specific binding of HIV-1 Gag to the 'packaging signal' in viral RNA
Selective packaging of HIV-1 genomic RNA (gRNA) requires the presence of a cis-acting RNA element called the ‘packaging signal’ (Ψ). However, the mechanism by which Ψ promotes selective packaging of the gRNA is not well understood. We used fluorescence correlation spectroscopy and quenching data to...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531834/ https://ncbi.nlm.nih.gov/pubmed/28726630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27055 |
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