Diagnostic potential of tumor DNA from ovarian cyst fluid

We determined whether the mutations found in ovarian cancers could be identified in the patients' ovarian cyst fluids. Tumor-specific mutations were detectable in the cyst fluids of 19 of 23 (83%) borderline tumors, 10 of 13 (77%) type I cancers, and 18 of 18 (100%) type II cancers. In contrast...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Yuxuan, Sundfeldt, Karin, Mateoiu, Constantina, Shih, Ie-Ming, Kurman, Robert J, Schaefer, Joy, Silliman, Natalie, Kinde, Isaac, Springer, Simeon, Foote, Michael, Kristjansdottir, Björg, James, Nathan, Kinzler, Kenneth W, Papadopoulos, Nickolas, Diaz, Luis A, Vogelstein, Bert
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946896/
https://ncbi.nlm.nih.gov/pubmed/27421040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15175
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