A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity

Vorinostat is an FDA-approved histone deacetylase inhibitor (HDACi) that has proven clinical success in some patients; however, it remains unclear why certain patients remain unresponsive to this agent and other HDACis. Constitutive STAT (signal transducer and activator of transcription) activation,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Falkenberg, K J, Newbold, A, Gould, C M, Luu, J, Trapani, J A, Matthews, G M, Simpson, K J, Johnstone, R W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946889/
https://ncbi.nlm.nih.gov/pubmed/26868908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.175
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados