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Crystal structure of an HIV assembly and maturation switch

Virus assembly and maturation proceed through the programmed operation of molecular switches, which trigger both local and global structural rearrangements to produce infectious particles. HIV-1 contains an assembly and maturation switch that spans the C-terminal domain (CTD) of the capsid (CA) regi...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Wagner, Jonathan M, Zadrozny, Kaneil K, Chrustowicz, Jakub, Purdy, Michael D, Yeager, Mark, Ganser-Pornillos, Barbie K, Pornillos, Owen
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946879/
https://ncbi.nlm.nih.gov/pubmed/27416583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17063
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