Crystal structure of an HIV assembly and maturation switch

Virus assembly and maturation proceed through the programmed operation of molecular switches, which trigger both local and global structural rearrangements to produce infectious particles. HIV-1 contains an assembly and maturation switch that spans the C-terminal domain (CTD) of the capsid (CA) regi...

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Bibliographic Details
Published in:eLife
Main Authors: Wagner, Jonathan M, Zadrozny, Kaneil K, Chrustowicz, Jakub, Purdy, Michael D, Yeager, Mark, Ganser-Pornillos, Barbie K, Pornillos, Owen
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946879/
https://ncbi.nlm.nih.gov/pubmed/27416583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17063
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