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Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy

There is an increasing interest in development of novel anticancer agents that target oncogenes. We have recently discovered that nuclear factor of activated T cells 1 (NFAT1) is a novel regulator of the Mouse Double Minute 2 (MDM2) oncogene and the NFAT1-MDM2 pathway has been implicated in human ca...

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Detalhes bibliográficos
Publicado no:J Biomed Res
Main Authors: Qin, Jiang-Jiang, Sarkar, Sushanta, Voruganti, Sukesh, Agarwal, Rajesh, Wang, Wei, Zhang, Ruiwen
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946323/
https://ncbi.nlm.nih.gov/pubmed/27533941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.30.20160018
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