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Analysis of copy number variation at DMBT1 and age-related macular degeneration
BACKGROUND: DMBT1 is a gene that shows extensive copy number variation (CNV) that alters the number of bacteria-binding domains in the protein and has been shown to activate the complement pathway. It lies next to the ARMS2/HTRA1 genes in a region of chromosome 10q26, where single nucleotide variant...
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| Publicado no: | BMC Med Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946147/ https://ncbi.nlm.nih.gov/pubmed/27416785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-016-0311-5 |
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