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Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease
Previous work has shown that the gene DMBT1, which encodes a large secreted epithelial glycoprotein known as salivary agglutinin, gp340, hensin or muclin, is an innate immune defence protein that binds bacteria. A deletion variant of DMBT1 has been previously associated with Crohn's disease, an...
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| Publié dans: | Eur J Hum Genet |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4851238/ https://ncbi.nlm.nih.gov/pubmed/26813944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.280 |
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