Genetic variation in complement regulators and susceptibility to age-related macular degeneration

OBJECTIVES: Age-related macular degeneration (AMD) is the commonest cause of blindness in Western populations. Risk is influenced by age, genetic and environmental factors. Complement activation appears to be important in the pathogenesis and associations have been found between AMD and genetic vari...

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Main Authors: Cipriani, Valentina, Matharu, Baljinder K., Khan, Jane C., Shahid, Humma, Stanton, Chloe M., Hayward, Caroline, Wright, Alan F., Bunce, Catey, Clayton, David G., Moore, Anthony T., Yates, John R.W.
格式: Artigo
語言:Inglês
出版: Elsevier 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657157/
https://ncbi.nlm.nih.gov/pubmed/22024702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2011.09.002
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