Chemo- and Stereoselective Transition-Metal-Free Amination of Amides with Azides

[Image: see text] The synthesis of α-amino carbonyl/carboxyl compounds is a contemporary challenge in organic synthesis. Herein, we present a stereoselective α-amination of amides employing simple azides that proceeds under mild conditions with release of nitrogen gas. The amide is used as the limit...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Tona, Veronica, de la Torre, Aurélien, Padmanaban, Mohan, Ruider, Stefan, González, Leticia, Maulide, Nuno
Format: Artigo
Language:Inglês
Published: American Chemical Society 2016
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945995/
https://ncbi.nlm.nih.gov/pubmed/27350334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04061
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