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Metal-free transannulation reaction of indoles with nitrostyrenes: a simple practical synthesis of 3-substituted 2-quinolones()

3-Substituted 2-quinolones are obtained via a novel, metal-free transannulation reaction of 2-substituted indoles with 2-nitroalkenes in polyphosphoric acid. The reaction can be used in conjunction with the Fisher indole synthesis offering a practical three-component heteroannulation methodology to...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Aksenov, Alexander V., Smirnov, Alexander N., Aksenov, Nicolai A., Aksenova, Inna V., Frolova, Liliya V., Kornienko, Alexander, Magedov, Igor V., Rubin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945960/
https://ncbi.nlm.nih.gov/pubmed/23999797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc45696j
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