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Glycosylation enables aesculin to activate Nrf2

Since aesculin, 6,7-dihydroxycoumarin-6-O-β-glucopyranoside, suppresses inflammation, we asked whether its anti-inflammatory activity is associated with the activation of nuclear factor-E2-related factor 2 (Nrf2), a key anti-inflammatory factor. Our results, however, show that aesculin marginally ac...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kim, Kyun Ha, Park, Hyunsu, Park, Hee Jin, Choi, Kyoung-Hwa, Sadikot, Ruxana T., Cha, Jaeho, Joo, Myungsoo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945939/
https://ncbi.nlm.nih.gov/pubmed/27417293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29956
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