A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction

TRIM5α from the rhesus macaque (TRIM5α(Rh)) is a restriction factor that shows strong activity against HIV-1. TRIM5α(Rh) binds specifically to HIV-1 capsid (CA) through its B30.2/PRYSPRY domain shortly after entry of the virus into the cytoplasm. Recently, three putative SUMO interacting motifs (SIM...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Nepveu-Traversy, Marie-Édith, Demogines, Ann, Fricke, Thomas, Plourde, Mélodie B., Riopel, Kathleen, Veillette, Maxime, Diaz-Griffero, Felipe, Sawyer, Sara L., Berthoux, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945854/
https://ncbi.nlm.nih.gov/pubmed/27441239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2015.e00056
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