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Noise-Induced Loss of Hair Cells and Cochlear Synaptopathy Are Mediated by the Activation of AMPK

Noise-induced hearing loss (NIHL) is a major unresolved public health problem. Here, we investigate pathomechanisms of sensory hair cell death and suggest a novel target for protective intervention. Cellular survival depends upon maintenance of energy homeostasis, largely by AMP-activated protein ki...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hill, Kayla, Yuan, Hu, Wang, Xianren, Sha, Su-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945669/
https://ncbi.nlm.nih.gov/pubmed/27413159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0782-16.2016
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