Inhibition of Histone Methyltransferase G9a Attenuates Noise-Induced Cochlear Synaptopathy and Hearing Loss

Posttranslational modification of histones alters their interaction with DNA and nuclear proteins, influencing gene expression and cell fate. In this study, we investigated the effect of G9a (KMT1C, EHMT2), a major histone lysine methyltransferase encoded by the human EHMT2 gene and responsible for...

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Pubblicato in:J Assoc Res Otolaryngol
Autori principali: Xiong, Hao, Long, Haishan, Pan, Song, Lai, Ruosha, Wang, Xianren, Zhu, Yuanping, Hill, Kayla, Fang, Qiaojun, Zheng, Yiqing, Sha, Su-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513956/
https://ncbi.nlm.nih.gov/pubmed/30710318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-019-00714-6
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