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Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses

Mitochondria modulate cellular calcium homeostasis by the combined action of the mitochondrial calcium uniporter (MCU), a selective calcium entry channel, and the sodium calcium exchanger (NCLX), which extrudes calcium from mitochondria. In this study, we investigated MCU and NCLX in noise-induced h...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Wang, Xianren, Zhu, Yuanping, Long, Haishan, Pan, Song, Xiong, Hao, Fang, Qiaojun, Hill, Kayla, Lai, Ruosha, Yuan, Hu, Sha, Su-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331433/
https://ncbi.nlm.nih.gov/pubmed/30670946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00469
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