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Regulation of K-Ras4B Membrane Binding by Calmodulin

K-Ras4B is a membrane-bound small GTPase with a prominent role in cancer development. It contains a polybasic farnesylated C-terminus that is required for the correct localization and clustering of K-Ras4B in distinct membrane domains. PDEδ and the Ca(2+)-binding protein calmodulin (CaM) are known t...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Sperlich, Benjamin, Kapoor, Shobhna, Waldmann, Herbert, Winter, Roland, Weise, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945620/
https://ncbi.nlm.nih.gov/pubmed/27410739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.042
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