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Regulation of K-Ras4B Membrane Binding by Calmodulin
K-Ras4B is a membrane-bound small GTPase with a prominent role in cancer development. It contains a polybasic farnesylated C-terminus that is required for the correct localization and clustering of K-Ras4B in distinct membrane domains. PDEδ and the Ca(2+)-binding protein calmodulin (CaM) are known t...
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| Veröffentlicht in: | Biophys J |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945620/ https://ncbi.nlm.nih.gov/pubmed/27410739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.042 |
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