Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen Presenting Cell Features (Hybrid TANs) in Early-Stage Human Lung Cancer

Based on studies in mouse tumor models, granulocytes appear to play a tumor-promoting role. However, there are limited data about the phenotype and function of tumor-associated neutrophils (TANs) in humans. Here, we identify a subset of TANs that exhibited characteristics of both neutrophils and ant...

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Publicado no:Cancer Cell
Main Authors: Singhal, Sunil, Bhojnagarwala, Pratik S., O’Brien, Shaun, Moon, Edmund K, Garfall, Alfred L., Rao, Abhishek, Quatromoni, Jon G., Stephen, Tom Li, Litzky, Leslie, Deshpande, Charuhas, Feldman, Michael, Hancock, Wayne W., Conejo-Garcia, Jose R, Albelda, Steven M., Eruslanov, Evgeniy B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945447/
https://ncbi.nlm.nih.gov/pubmed/27374224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.06.001
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