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Statistical analysis of structural determinants for protein-DNA binding specificity

DNA-binding proteins play critical roles in biological processes including gene expression, DNA packaging and DNA repair. They bind to DNA target sequences with different degrees of binding specificity, ranging from highly specific to non-specific. Alterations of DNA-binding specificity, due to eith...

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Détails bibliographiques
Publié dans:Proteins
Auteurs principaux: Corona, Rosario I., Guo, Jun-tao
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945413/
https://ncbi.nlm.nih.gov/pubmed/27147539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25061
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