Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4

The molecular mechanisms underlying the regulation of pluripotency by cellular metabolism in human embryonic stem cells (hESCs) are not fully understood. We found that high levels of glutamine metabolism are essential to prevent degradation of OCT4, a key transcription factor regulating hESC pluripo...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Marsboom, Glenn, Zhang, Guo-Fang, Pohl-Avila, Nicole, Zhang, Yanmin, Yuan, Yang, Kang, Hojin, Hao, Bo, Brunengraber, Henri, Malik, Asrar B., Rehman, Jalees
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945388/
https://ncbi.nlm.nih.gov/pubmed/27346346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.089
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