Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4

The molecular mechanisms underlying the regulation of pluripotency by cellular metabolism in human embryonic stem cells (hESCs) are not fully understood. We found that high levels of glutamine metabolism are essential to prevent degradation of OCT4, a key transcription factor regulating hESC pluripo...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Marsboom, Glenn, Zhang, Guo-Fang, Pohl-Avila, Nicole, Zhang, Yanmin, Yuan, Yang, Kang, Hojin, Hao, Bo, Brunengraber, Henri, Malik, Asrar B., Rehman, Jalees
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945388/
https://ncbi.nlm.nih.gov/pubmed/27346346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.089
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares