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Amyotrophic Lateral Sclerosis Type 20 - In Silico Analysis and Molecular Dynamics Simulation of hnRNPA1

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that affects the upper and lower motor neurons. 5–10% of cases are genetically inherited, including ALS type 20, which is caused by mutations in the hnRNPA1 gene. The goals of this work are to analyze the effects of non-synonym...

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Publicat a:PLoS One
Autors principals: Krebs, Bruna Baumgarten, De Mesquita, Joelma Freire
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945010/
https://ncbi.nlm.nih.gov/pubmed/27414033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158939
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