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Amyotrophic Lateral Sclerosis Type 20 - In Silico Analysis and Molecular Dynamics Simulation of hnRNPA1

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that affects the upper and lower motor neurons. 5–10% of cases are genetically inherited, including ALS type 20, which is caused by mutations in the hnRNPA1 gene. The goals of this work are to analyze the effects of non-synonym...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Krebs, Bruna Baumgarten, De Mesquita, Joelma Freire
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945010/
https://ncbi.nlm.nih.gov/pubmed/27414033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158939
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