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Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality

Fibroblastic reticular cells (FRCs) form the cellular scaffold of lymph nodes (LNs) and establish distinct microenvironmental niches to provide key molecules that drive innate and adaptive immune responses and control immune regulatory processes. Here, we have used a graph theory-based systems biolo...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Novkovic, Mario, Onder, Lucas, Cupovic, Jovana, Abe, Jun, Bomze, David, Cremasco, Viviana, Scandella, Elke, Stein, Jens V., Bocharov, Gennady, Turley, Shannon J., Ludewig, Burkhard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945005/
https://ncbi.nlm.nih.gov/pubmed/27415420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002515
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