Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality

Fibroblastic reticular cells (FRCs) form the cellular scaffold of lymph nodes (LNs) and establish distinct microenvironmental niches to provide key molecules that drive innate and adaptive immune responses and control immune regulatory processes. Here, we have used a graph theory-based systems biolo...

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Publicat a:PLoS Biol
Autors principals: Novkovic, Mario, Onder, Lucas, Cupovic, Jovana, Abe, Jun, Bomze, David, Cremasco, Viviana, Scandella, Elke, Stein, Jens V., Bocharov, Gennady, Turley, Shannon J., Ludewig, Burkhard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945005/
https://ncbi.nlm.nih.gov/pubmed/27415420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002515
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