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Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability

Dengue is the most prevalent arboviral disease in humans and a major public health problem worldwide. Systemic plasma leakage, leading to hypovolemic shock and potentially fatal complications, is a critical determinant of dengue severity. Recently, we and others described a novel pathogenic effect o...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Puerta-Guardo, Henry, Glasner, Dustin R., Harris, Eva
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944995/
https://ncbi.nlm.nih.gov/pubmed/27416066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005738
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