CdtR Regulates TcdA and TcdB Production in Clostridium difficile

Clostridium difficile is a global health burden and the leading cause of antibiotic-associated diarrhoea worldwide, causing severe gastrointestinal disease and death. Three well characterised toxins are encoded by this bacterium in two genetic loci, specifically, TcdB (toxin B) and TcdA (toxin A) in...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Lyon, Shelley A., Hutton, Melanie L., Rood, Julian I., Cheung, Jackie K., Lyras, Dena
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944984/
https://ncbi.nlm.nih.gov/pubmed/27414650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005758
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