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Dermal fibroblasts induce cell cycle arrest and block epithelial–mesenchymal transition to inhibit the early stage melanoma development

Stromal fibroblasts are an integral part of the tumor stroma and constantly interact with cancer cells to promote their initiation and progression. However, the role and function of dermal fibroblasts during the early stage of melanoma development remain poorly understood. We, therefore, designed a...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Zhou, Linli, Yang, Kun, Randall Wickett, R., Zhang, Yuhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944884/
https://ncbi.nlm.nih.gov/pubmed/27061029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.707
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