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Dermal fibroblasts induce cell cycle arrest and block epithelial–mesenchymal transition to inhibit the early stage melanoma development

Stromal fibroblasts are an integral part of the tumor stroma and constantly interact with cancer cells to promote their initiation and progression. However, the role and function of dermal fibroblasts during the early stage of melanoma development remain poorly understood. We, therefore, designed a...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Zhou, Linli, Yang, Kun, Randall Wickett, R., Zhang, Yuhang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944884/
https://ncbi.nlm.nih.gov/pubmed/27061029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.707
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