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Convergent and Biomimetic Enantioselective Total Synthesis of (−)-Communesin F

The first biomimetic enantioselective total synthesis of (−)-communesin F based on a late-stage heterodimerization and aminal exchange is described. Our synthesis features the expedient diazene–directed assembly of two advanced fragments to secure the congested C3a–C3a′ linkage in three steps, follo...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Lathrop, Stephen P., Pompeo, Matthew, Chang, Wen-Tau T., Movassaghi, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944760/
https://ncbi.nlm.nih.gov/pubmed/27244250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04072
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