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Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven
[Image: see text] We report our full account of the enantioselective total synthesis of (−)-acylfulvene (1) and (−)-irofulven (2), which features metathesis reactions for the rapid assembly of the molecular framework of these antitumor agents. We discuss (1) the application of an Evans’ Cu-catalyzed...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805080/ https://ncbi.nlm.nih.gov/pubmed/19938810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo901926z |
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