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Clathrin Assembly Regulated by Adaptor Proteins in Coarse-Grained Models

The assembly of clathrin triskelia into polyhedral cages during endocytosis is regulated by adaptor proteins (APs). We explore how APs achieve this by developing coarse-grained models for clathrin and AP2, employing a Monte Carlo click interaction, to simulate their collective aggregation behavior....

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Giani, Matteo, den Otter, Wouter K., Briels, Wim J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944722/
https://ncbi.nlm.nih.gov/pubmed/27410749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.003
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