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Asymmetry as the Key to Clathrin Cage Assembly

The self-assembly of clathrin proteins into polyhedral cages is simulated for the first time (to our knowledge) by introducing a coarse-grain triskelion particle modeled after clathrin's characteristic shape. The simulations indicate that neither this shape, nor the antiparallel binding of four...

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Hlavní autoři: den Otter, Wouter K., Renes, Marten R., Briels, W.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920741/
https://ncbi.nlm.nih.gov/pubmed/20713007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.011
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