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High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

One limit to successful receptor-mediated gene delivery is the exit of the endocytosed material from the endosome. We demonstrate here the delivery of marker genes to tissue culture cells using a modification of the receptor-mediated gene delivery technique that exploits the endosomolytic activity o...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Cotten, M, Wagner, E, Zatloukal, K, Phillips, S, Curiel, D T, Birnstiel, M L
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1352882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6094
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