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High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

One limit to successful receptor-mediated gene delivery is the exit of the endocytosed material from the endosome. We demonstrate here the delivery of marker genes to tissue culture cells using a modification of the receptor-mediated gene delivery technique that exploits the endosomolytic activity o...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Cotten, M, Wagner, E, Zatloukal, K, Phillips, S, Curiel, D T, Birnstiel, M L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1992
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1352882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6094
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