Targeted Mutagenesis of Guinea Pig Cytomegalovirus Using CRISPR/Cas9-Mediated Gene Editing

The cytomegaloviruses (CMVs) are among the most genetically complex mammalian viruses, with viral genomes that often exceed 230 kbp. Manipulation of cytomegalovirus genomes is largely performed using infectious bacterial artificial chromosomes (BACs), which necessitates the maintenance of the viral...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Bierle, Craig J., Anderholm, Kaitlyn M., Wang, Jian Ben, McVoy, Michael A., Schleiss, Mark R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Genome Replication and Regulation of Viral Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944286/
https://ncbi.nlm.nih.gov/pubmed/27226370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00139-16
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