Stability of HIV Frameshift Site RNA Correlates with Frameshift Efficiency and Decreased Virus Infectivity

Human immunodeficiency virus (HIV) replication is strongly dependent upon a programmed ribosomal frameshift. Here we investigate the relationships between the thermodynamic stability of the HIV type 1 (HIV-1) RNA frameshift site stem-loop, frameshift efficiency, and infectivity, using pseudotyped HI...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Garcia-Miranda, Pablo, Becker, Jordan T., Benner, Bayleigh E., Blume, Alexander, Sherer, Nathan M., Butcher, Samuel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Structure and Assembly
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944283/
https://ncbi.nlm.nih.gov/pubmed/27194769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00149-16
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