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Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

Eye diseases characterized by excessive angiogenesis such as wet age-related macular degeneration, proliferative diabetic retinopathy, and retinopathy of prematurity are major causes of blindness. Cremastranone is an anti-angiogenic, naturally occurring homoisoflavanone with efficacy in retinal and...

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Veröffentlicht in:J Med Chem
Hauptverfasser: Basavarajappa, Halesha D., Lee, Bit, Lee, Hyungjun, Sulaiman, Rania S., An, Hongchan, Magaña, Carlos, Shadmand, Mehdi, Vayl, Alexandra, Rajashekhar, Gangaraju, Kim, Eun-Yeong, Suh, Young-Ger, Lee, Kiho, Seo, Seung-Yong, Corson, Timothy W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944207/
https://ncbi.nlm.nih.gov/pubmed/26035340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00449
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