IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin

B cells participate in immune surveillance in human circulation and tissues, including tumors such as melanoma. By contrast, the role of humoral responses in cutaneous immunity is underappreciated. We report circulating skin-homing CD22+CLA+B cells in healthy volunteers and melanoma patients (n = 73...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Saul, Louise, Ilieva, Kristina M., Bax, Heather J., Karagiannis, Panagiotis, Correa, Isabel, Rodriguez-Hernandez, Irene, Josephs, Debra H., Tosi, Isabella, Egbuniwe, Isioma U., Lombardi, Sara, Crescioli, Silvia, Hobbs, Carl, Villanova, Federica, Cheung, Anthony, Geh, Jenny L. C., Healy, Ciaran, Harries, Mark, Sanz-Moreno, Victoria, Fear, David J., Spicer, James F., Lacy, Katie E., Nestle, Frank O., Karagiannis, Sophia N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944184/
https://ncbi.nlm.nih.gov/pubmed/27411958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29736
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi