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Divalent Ion Dependent Conformational Changes in an RNA Stem-Loop Observed by Molecular Dynamics

[Image: see text] We compare the performance of five magnesium (Mg(2+)) ion models in simulations of an RNA stem loop which has an experimentally determined divalent ion dependent conformational shift. We show that despite their differences in parametrization and resulting van der Waals terms, inclu...

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Publicat a:J Chem Theory Comput
Autors principals: Bergonzo, Christina, Hall, Kathleen B., Cheatham, Thomas E.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944181/
https://ncbi.nlm.nih.gov/pubmed/27294370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b00173
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