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Initial Binding of Ions to the Interhelical Loops of Divalent Ion Transporter CorA: Replica Exchange Molecular Dynamics Simulation Study

Crystal structures of Thermotoga maritima magnesium transporter CorA, reported in 2006, revealed its homo-pentameric constructions. However, the structure of the highly conserved extracellular interhelical loops remains unsolved, due to its high flexibility. We have explored the configurations of th...

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Autors principals: Zhang, Tong, Mu, Yuguang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431404/
https://ncbi.nlm.nih.gov/pubmed/22952795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043872
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