A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125

The activity of RING ubiquitin ligases (E3s) depends on an interaction between the RING domain and ubiquitin conjugating enzymes (E2), but posttranslational events or additional structural elements, yet largely undefined, are frequently required to enhance or regulate activity. Here, we show for the...

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發表在:Sci Rep
Main Authors: Bijlmakers, Marie-José, Teixeira, João M. C., Boer, Roeland, Mayzel, Maxim, Puig-Sàrries, Pilar, Karlsson, Göran, Coll, Miquel, Pons, Miquel, Crosas, Bernat
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944129/
https://ncbi.nlm.nih.gov/pubmed/27411375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29232
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