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A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125

The activity of RING ubiquitin ligases (E3s) depends on an interaction between the RING domain and ubiquitin conjugating enzymes (E2), but posttranslational events or additional structural elements, yet largely undefined, are frequently required to enhance or regulate activity. Here, we show for the...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bijlmakers, Marie-José, Teixeira, João M. C., Boer, Roeland, Mayzel, Maxim, Puig-Sàrries, Pilar, Karlsson, Göran, Coll, Miquel, Pons, Miquel, Crosas, Bernat
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944129/
https://ncbi.nlm.nih.gov/pubmed/27411375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29232
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