A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

We performed a quantitative analysis of the HLA restriction, antigen and epitope specificity of human pathogen specific responses in healthy individuals infected with M. tuberculosis (Mtb), in a South African cohort as a test case. The results estimate the breadth of T cell responses for the first t...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Lindestam Arlehamn, Cecilia S., McKinney, Denise M., Carpenter, Chelsea, Paul, Sinu, Rozot, Virginie, Makgotlho, Edward, Gregg, Yolande, van Rooyen, Michele, Ernst, Joel D., Hatherill, Mark, Hanekom, Willem A., Peters, Bjoern, Scriba, Thomas J., Sette, Alessandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943605/
https://ncbi.nlm.nih.gov/pubmed/27409590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005760
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