A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

We performed a quantitative analysis of the HLA restriction, antigen and epitope specificity of human pathogen specific responses in healthy individuals infected with M. tuberculosis (Mtb), in a South African cohort as a test case. The results estimate the breadth of T cell responses for the first t...

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Publicado en:PLoS Pathog
Main Authors: Lindestam Arlehamn, Cecilia S., McKinney, Denise M., Carpenter, Chelsea, Paul, Sinu, Rozot, Virginie, Makgotlho, Edward, Gregg, Yolande, van Rooyen, Michele, Ernst, Joel D., Hatherill, Mark, Hanekom, Willem A., Peters, Bjoern, Scriba, Thomas J., Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943605/
https://ncbi.nlm.nih.gov/pubmed/27409590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005760
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