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Founder and Recurrent Mutations in BRCA1 and BRCA2 Genes in Latin American Countries: State of the Art and Literature Review
BACKGROUND. Numerous epidemiological factors affect the probability of developing breast or ovarian cancer, but no predictor is as determinant as inheriting a mutation in BRCA1 or BRCA2. The concept of the founder effect explains the reduced genetic variability in some populations, according to the...
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| 發表在: | Oncologist |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
AlphaMed Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4943386/ https://ncbi.nlm.nih.gov/pubmed/27286788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0416 |
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