Low Prevalence of the Four Common Colombian Founder Mutations in BRCA1 and BRCA2 in Early‐Onset and Familial Afro‐Colombian Patients with Breast Cancer

BACKGROUND. Inherited mutations in the breast cancer susceptibility genes BRCA1 and BRCA2 (BRCA1/2) confer high risks of breast and ovarian cancer. In Colombian Hispanic families, four common BRCA1/2 founder mutations have previously been identified. Because nothing is known about the contribution o...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Vargas, Elizabeth, Torres Lopez, Diana Maria, de Deugd, Robert, Gil, Fabian, Nova, Alejandra, Mora, Lina, Viaña, Luis Fernando, Hernandez, José David, Bruges, Ricardo, Hamann, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Global Health and Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656434/
https://ncbi.nlm.nih.gov/pubmed/30541753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0346
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