Nitrite Therapy Improves Left Ventricular Function During Heart Failure via Restoration of Nitric Oxide (NO) Mediated Cytoprotective Signaling

RATIONALE: Nitric oxide (NO) bioavailability is reduced in the setting of heart failure. Nitrite (NO(2)) is a critically important NO intermediate that is metabolized to NO during pathological states. We have previously demonstrated that sodium nitrite ameliorates acute myocardial ischemia/reperfusi...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Bhushan, Shashi, Kondo, Kazuhisa, Polhemus, David, Otsuka, Hiroyuki, Nicholson, Chad, Tao, Ya-Xiong, Huang, Hui, Georgiopoulou, Vasiliki V., Murohara, Toyoaki, Calvert, John W., Butler, Javed, Lefer, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943032/
https://ncbi.nlm.nih.gov/pubmed/24599803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.301475
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