H(2)S Protects Against Pressure Overload Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase (eNOS)

INTRODUCTION: Cystathionine gamma-lyase (CSE) produces H(2)S via enzymatic conversion of L-cysteine and plays a critical role in cardiovascular homeostasis. We investigated the effects of genetic modulation of CSE and exogenous H(2)S therapy in the setting of pressure overload-induced heart failure....

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Detalhes bibliográficos
Main Authors: Kondo, Kazuhisa, Bhushan, Shashi, King, Adrienne L., Prabhu, Sumanth D., Hamid, Tariq, Koenig, Steven, Murohara, Toyoaki, Predmore, Benjamin L., Gojon, Gabriel, Wang, Rui, Karusula, Naveena, Nicholson, Chad K., Calvert, John W., Lefer, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670187/
https://ncbi.nlm.nih.gov/pubmed/23393010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.000855
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